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Pharmasave Kensington

Compounded Combination Creams for Skin Conditions in Brampton

8 min read

Some skin prescriptions combine several ingredients in a single cream or ointment. Here is why prescribers write them, how the pharmacy prepares them, and how to use them well.

In this article

Skin problems are rarely tidy. A rash in a skin fold may be inflamed and infected with yeast at the same time. A patch of thickened skin on the foot may need softening before any medicine can penetrate. An itchy scalp condition may need something to calm inflammation and something to control flaking. When a skin problem has more than one part, a prescriber may want to treat more than one part at once.

One way to do that is to prescribe two or three separate products and ask the patient to apply them in sequence. Another is to ask a compounding pharmacy to combine the ingredients into a single cream, ointment, lotion or solution. Pharmasave Kensington in Brampton lists dermatology among the specialty areas on its compounded prescriptions page, and its searchable general compounds list includes many combination skin preparations. This guide explains why these are prescribed and how to use them sensibly.

Why a prescriber might combine ingredients

There are several reasons a dermatologist, family doctor or nurse practitioner might write for a combination product:

  • Treating two problems at once. An anti-inflammatory ingredient and an antifungal, for example, might be combined when both inflammation and a fungal infection are present.
  • Simplifying the routine. One product applied twice a day is easier to remember than three products applied in a certain order.
  • Adjusting strength. A prescriber might want a particular concentration of an ingredient that isn’t commercially available.
  • Adding comfort. Ingredients such as menthol or camphor are sometimes added to help with itching.
  • Improving penetration. Ingredients like salicylic acid can help soften thick, scaly skin so other medicines work better.

The prescriber decides what to combine and in what strength, based on their assessment of your skin. The pharmacist checks that the combination is compatible and can be prepared in a stable form.

Examples of the kinds of combinations prepared

Browsing the store’s general compounds list gives a sense of the variety. It includes combinations such as a mild corticosteroid like hydrocortisone mixed into an antifungal cream, antibiotics added to corticosteroid lotions, menthol and camphor added to corticosteroid creams for itch, salicylic acid in petrolatum at various strengths for thickened skin, and medicated shampoos and topical solutions.

These examples illustrate what is possible; they are not recommendations. A combination suitable for one person’s rash could be wrong for another’s. Corticosteroids, for instance, vary widely in strength, and using a potent one on the face or in skin folds without direction can cause problems. That’s why every combination product should be prescribed for you specifically.

Helping your prescriber see the whole picture

Skin appointments are often short, and a rash can look different on the day of the visit than it did at its worst. You can make the most of the time by arriving prepared. Before the appointment, jot down:

  • When the problem started and whether it comes and goes.
  • What seems to trigger or worsen it: heat, sweat, cold weather, certain soaps, new clothing, stress or contact with particular materials.
  • Every product you’ve already tried, including over-the-counter creams, home remedies, oils and anything recommended by friends or family, and what happened with each.
  • Whether anyone else in the household has a similar rash.
  • Photos of the area when it was at its worst.

Bring the actual products or clear photos of their labels if you can. Many people have tried several creams before they see a prescriber, and some of those products, including strong corticosteroid creams brought from overseas or shared by relatives, can change how a rash looks. Being open about what you’ve used helps your prescriber choose the right ingredients and avoid duplicating something that didn’t work.

If you have darker skin, mention any changes in pigmentation, such as lighter or darker patches, as these can be an important part of how skin conditions present and heal. Ask how the treatment might affect skin colour and what to watch for.

How the pharmacy prepares a combination cream

When the prescription arrives, the pharmacist considers whether the ingredients can be mixed without breaking down or separating, which base or commercial product will serve as the vehicle, what the final concentration of each ingredient will be, and how long the product will remain stable. Sometimes two commercial creams are mixed in a set ratio; other times an active ingredient is added to a base.

The base matters, because it influences how the product feels and how well the ingredients reach the skin. The store explains the role of different bases, including options for psoriasis-prone and acne-prone skin, on its compounding bases page.

The result is labelled with each ingredient and its strength, directions for use, and a use-by date. Combination products often have shorter use-by dates than the original commercial creams, because mixing can affect stability.

Using a combination product correctly

Good technique helps a combination product do its job and reduces side effects. General tips include:

  1. Apply only to the area your prescriber specified. Don’t spread it to new areas without checking.
  2. Use a thin layer unless directed otherwise. More isn’t better with most medicated creams.
  3. Follow the frequency and duration on the label. Many products containing corticosteroids are intended for limited periods. If the label says “for two weeks,” ask before continuing beyond that.
  4. Wash your hands after applying, unless your hands are being treated.
  5. Wait before layering other products, like moisturisers or sunscreen, and ask the pharmacist how long.
  6. Keep it away from your eyes unless it was specifically prescribed for the eyelid area.

Special care for the face, skin folds and children

Some areas of skin are thinner and absorb medicine more readily: the face, eyelids, armpits, groin and areas under the breasts. Infants and young children also have thinner skin and a larger skin surface relative to body weight. A product that’s suitable for a thick patch on an adult’s elbow may be too strong elsewhere.

If a combination cream has been prescribed for one family member, don’t use it on someone else, even if the rash looks similar. This is a common temptation in large households where several people share a bathroom cabinet. A rash that resembles eczema could be a fungal infection, and the wrong product can make some conditions worse.

How to tell if it’s working

Skin conditions take time to improve, and some get slightly worse before they get better. Take photographs of the area in consistent lighting every few days. This makes it easier to see gradual change and gives your prescriber useful information at follow-up.

Contact your prescriber or pharmacist if the rash spreads, becomes more painful, oozes, develops pus, or doesn’t improve in the timeframe you were given. Also report new burning, stinging, thinning of the skin, or colour changes at the application site.

Once a rash clears, ask what to do next. Some prescribers want the product stopped immediately, others prefer a gradual reduction, and some recommend switching to a plain moisturiser to help maintain the skin barrier. Knowing the plan ahead of time stops you from either abandoning treatment too early or continuing a medicated product longer than intended.

Storage and use-by dates

Store the product as the label directs, usually at room temperature away from heat and moisture. Bathrooms can be humid; a bedroom drawer or cupboard may be better if your instructions allow. Don’t use the product after the use-by date, even if there’s some left. If you find you’re running out much faster or slower than expected, you may be applying too much or too little, so ask the pharmacist.

Plan prescription refills with some notice. Compounded products are prepared on demand and may not be available for immediate pickup.

A brief Q&A on combination skin products

Is a compounded combination stronger than a regular cream? Not necessarily. It depends on the ingredients and strengths chosen. Read the label and ask.

Can I buy the same thing over the counter? Some single ingredients are available without a prescription, but prescribed combinations and strengths generally aren’t. Don’t try to recreate a combination by mixing products at home.

Will my insurance cover it? Coverage of compounded skin products varies by plan. Ask the pharmacy about the cost and check with your insurer.

Can I use it on a new rash in a different place? Check with your prescriber first. A different rash may need different treatment.

Ask Pharmasave Kensington about your skin prescription

If you’ve been prescribed a combination cream, or your prescriber has mentioned compounding for a stubborn skin condition, the pharmacy team can explain how it’s made, how to apply it and how to store it. If you’re using several topical products at once, a medication review can help you organise them.

Visit Pharmasave Kensington at 106-18 Kensington Road, Brampton, ON L6T 4S5, or ring (905) 792-3100 with questions. Store details are on the contact page, and you can request time with a pharmacist through the booking page.

The information here is general. Use prescription skin products only as directed, and consult your prescriber about any rash that worsens or doesn’t improve.

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